Black Box Warning

Black Box Warning: Increased risk of suicidal thoughts in children, adolescents, and young adults under 24 years.

What this means:A black box warning is the FDA's strongest required safety notice. It signals a serious or life-threatening risk. Patients should review this with their prescriber before starting, continuing, or switching Duloxetine.

Other warnings & precautions

Hepatotoxicity: Duloxetine should not be used in patients with substantial alcohol use or chronic liver disease. Cases of serious liver injury reported.
Hypertension: Due to noradrenergic activity, blood pressure should be measured before initiation and monitored periodically.
Discontinuation Syndrome: Taper gradually to minimize dizziness, nausea, headache, and 'electric shock' sensations.
Narrow-Angle Glaucoma: Can precipitate angle-closure glaucoma due to mydriasis.

Black Box Warning

Black Box Warning: Increased risk of suicidal thoughts in children, adolescents, and young adults under 24 years.

Other warnings & precautions

Hepatotoxicity: Duloxetine should not be used in patients with substantial alcohol use or chronic liver disease. Cases of serious liver injury reported.
Hypertension: Due to noradrenergic activity, blood pressure should be measured before initiation and monitored periodically.
Discontinuation Syndrome: Taper gradually to minimize dizziness, nausea, headache, and 'electric shock' sensations.
Narrow-Angle Glaucoma: Can precipitate angle-closure glaucoma due to mydriasis.

Duloxetine Black Box Warning

Black Box Warning

Other warnings & precautions

Duloxetine Black Box Warning

Black Box Warning

Other warnings & precautions