Complete dosing information for methotrexate
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
RA: 7.5-25 mg weekly; Cancer: varies by regimen; Psoriasis: 10-25 mg weekly
0.3-1 mg/kg weekly depending on indication
CrCl 10-50: reduce dose 25-50%; CrCl <10: contraindicated
Cirrhosis/fibrosis: contraindicated; avoid in significant liver disease