Complete dosing information for suzetrigine
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Initial loading dose: 100 mg orally once, taken at least 1 hour before or 2 hours after a meal. Maintenance dose: 50 mg orally every 12 hours (twice daily), taken at least 1 hour before or 2 hours after a meal. Maximum duration of use studied in clinical trials: up to 14 days. No dose adjustment is required for mild-to-moderate renal impairment. No dose adjustment is required for mild-to-moderate hepatic impairment (Child-Pugh A or B). Use in severe hepatic impairment (Child-Pugh C) is not recommended due to significantly increased drug exposure.
Not approved for pediatric use. Safety and effectiveness in patients under 18 years of age have not been established.