6 known interactions • 3 major • 3 moderate • 0 minor
Always disclose all medications to your healthcare providers — prescription medicines, OTC medications, vitamins, and herbal supplements. This list may not include every possible interaction. Use our Medicine Interaction Checker to screen your complete medication list.
Potentially life-threatening or causing permanent damage. Avoid combination.
May worsen condition or require dose adjustment. Monitor closely.
Usually limited clinical effect. Manage with routine monitoring.
MAOIs
Potentially fatal serotonin syndrome. 14-day washout required before or after MAOI use.
Management: ABSOLUTE CONTRAINDICATION.
Pimozide
QTc prolongation risk. Contraindicated.
Management: Do not use together.
Linezolid / IV methylene blue
Serotonin syndrome risk.
Management: Contraindicated.
Cimetidine
Inhibits escitalopram metabolism; may increase escitalopram levels by up to 70%.
Management: Reduce escitalopram dose if cimetidine added.
Warfarin
May increase anticoagulant effect and bleeding risk.
Management: Monitor PT/INR closely.
NSAIDs and aspirin
Increased GI bleeding risk due to additive antiplatelet effects.
Management: Use with caution; consider PPI if concurrent use necessary.
Always ask your pharmacist about potential interactions with food, alcohol, and supplements specific to Escitalopram. Some medicines have significant interactions with grapefruit juice, high-fat meals, dairy products, or vitamin K-rich foods.