Complete dosing information for doxycycline hyclate
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Standard infections: 100mg twice daily or 200mg once daily; Lyme disease: 100mg twice daily for 10–21 days (early), 14–28 days (disseminated); RMSF: 100mg twice daily for at least 3 days after fever subsides (minimum 5–7 days); Malaria prophylaxis: 100mg once daily starting 1–2 days before travel; continue 4 weeks after leaving; Chlamydia: 100mg twice daily for 7 days; Acne: 50–100mg once or twice daily; Rosacea (Oracea): 40mg once daily in morning
CONTRAINDICATED in children <8 years (permanent tooth discoloration). ≥8 years: 2.2mg/kg twice daily (max 100mg/dose). Exception: RMSF — benefit outweighs risk at any age.
No dose adjustment required.
Use with caution in severe hepatic disease.