Complete dosing information for acetylsalicylic acid
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Cardiovascular prevention (secondary): 75–100mg once daily (low-dose aspirin); Acute MI (loading dose): 325mg chewed immediately (non-enteric coated) — call 911 first; Post-stent (DAPT): 81mg daily (with clopidogrel or other P2Y12 inhibitor for 1 year); Pain/fever: 325–1,000mg every 4–6 hours; max 4g/day; Anti-inflammatory (arthritis): 3,000–6,000mg/day in divided doses (rarely used — GI toxicity)
CONTRAINDICATED in children and adolescents for viral illnesses (risk of Reye's syndrome). Kawasaki disease exception: 80–100mg/kg/day (high dose, anti-inflammatory phase) then 3–5mg/kg/day (antiplatelet phase).
Avoid in severe renal impairment (CrCl <10 mL/min). Accumulation of salicylates in renal impairment.
Use with caution in severe hepatic disease due to coagulation effects.