Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
Sedation/drowsiness (41–77%)
Dizziness (29%)
Memory impairment/amnesia
Cognitive impairment
Coordination difficulties/ataxia
Slurred speech
Fatigue
Dependence and withdrawal syndrome (one of the most severe medicine withdrawal syndromes — potentially life-threatening)
Respiratory depression (especially with opioids or alcohol)
Paradoxical agitation/aggression (especially in elderly and children)
Falls and fractures (elderly)
Abuse and misuse
Mania induction in patients with bipolar disorder
Disinhibition behaviors (rare but reported)
Anterograde amnesia with high doses
Hypersensitivity reactions
Like all medications, Alprazolam can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: