Complete dosing information for alprazolam
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Anxiety (immediate release): 0.25–0.5mg 3 times daily; may increase every 3–4 days; usual range 0.5–4mg/day; maximum 4mg/day; Panic disorder (IR): 0.5mg 3 times daily initially; may increase up to 1–10mg/day (mean effective dose ~5–6mg/day); Panic disorder (XR): 0.5–1mg once daily in morning; may titrate by 1mg/day every 3–4 days; range 3–6mg/day
Safety and efficacy not established in patients <18 years. Generally avoided.
No dose adjustment required. Use with caution.
Use with caution; reduce dose in hepatic impairment. Avoid in severe hepatic disease.