Complete dosing information for sertraline
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Major Depressive Disorder: Initial dose 50 mg once daily; may increase in increments of 25–50 mg at intervals of at least 1 week; usual effective dose 50–200 mg/day; maximum dose 200 mg/day. OCD: Initial 50 mg once daily; titrate to 50–200 mg/day. Panic Disorder: Initial 25 mg once daily for 1 week, then increase to 50 mg once daily; titrate up to 200 mg/day as needed. PTSD: Initial 25 mg once daily; increase to 50 mg after 1 week; range 50–200 mg/day. Social Anxiety Disorder: Initial 25 mg once daily; increase to 50 mg after 1 week; range 50–200 mg/day. PMDD: 50 mg/day either continuously or limited to the luteal phase (14 days before anticipated menstruation); may titrate up to 150 mg/day for continuous dosing or 100 mg/day for luteal phase dosing (after 3 cycles).
OCD (ages 6–12): Initial 25 mg once daily; titrate at weekly intervals; usual range 25–200 mg/day; maximum 200 mg/day. OCD (ages 13–17): Initial 50 mg once daily; usual range 50–200 mg/day; maximum 200 mg/day. Not approved for MDD, panic disorder, PTSD, social anxiety disorder, or PMDD in patients under 18 years of age.