Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
ADVERSE REACTIONS There have been reports of hypersensitivity reactions and Parkinson-like symptoms.
There have been instances of hypotension reported following parenteral administration to surgical patients.
There have been reports of blood dyscrasias, blurring of vision, coma, convulsions, depression of mood, diarrhea, disorientation, dizziness, drowsiness, headache, jaundice, muscle cramps and opisthotonos.
If these occur, the administration of the drug should be discontinued.
Allergic-type skin reactions have been observed;
therefore, the drug should be discontinued at the first sign of sensitization.
While these symptoms will usually disappear spontaneously, symptomatic treatment may be indicated in some cases.
For medical advice about adverse reactions contact your medical professional.
To report SUSPECTED ADVERSE REACTIONS, contact Par Pharmaceutical, Inc.
at 1-800-828-9393 or FDA at 1-800-FDA-1088 (1-800-332-1088) or www.fda.gov/medwatch.
WARNINGS Tigan® may produce drowsiness.
Patients should not operate motor vehicles or other dangerous machinery until their individual responses have been determined.
Usage in Pregnancy Trimethobenzamide hydrochloride was studied in reproduction experiments in rats and rabbits and no teratogenicity was suggested.
The only effects observed were an increased percentage of embryonic resorptions or stillborn pups in rats administered 20 mg and 100 mg/kg and increased resorptions in rabbits receiving 100 mg/kg.
In each study these adverse effects were attributed to one or two dams.
Like all medications, Tigan(r) (trimethobenzamide Hydrochloride) can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: