Complete dosing information for semaglutide
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Oral (Rybelsus): Start 3 mg once daily for 30 days, increase to 7 mg once daily, then to 14 mg once daily if needed. Injectable (Ozempic): Start 0.25 mg SC once weekly for 4 weeks, increase to 0.5 mg weekly; may increase to 1–2 mg weekly.
Not approved for pediatric use.
No dose adjustment required for mild-moderate renal impairment.
No dose adjustment required.