Complete dosing information for prednisone
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
Anti-inflammatory/immunosuppressive: 5–60mg/day in single or divided doses; dose varies widely by indication; Asthma exacerbation (short course): 40–60mg/day for 5–7 days (burst therapy — no taper needed for ≤5 days); Adrenal insufficiency (physiologic replacement): 5–7.5mg/day in divided doses (hydrocortisone generally preferred); Severe autoimmune disease: 1–2mg/kg/day; taper slowly once remission achieved
Varies by indication; typically 0.5–2mg/kg/day. Weight-based dosing is essential.
No dose adjustment typically needed, but fluid retention effects may be more pronounced.
Caution in severe hepatic disease — conversion of prednisone to prednisolone may be impaired. Use prednisolone directly in severe liver disease.