Complete dosing information for METHYLNALTREXONE BROMIDE
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
2 DOSAGE AND ADMINISTRATION Administration Instructions ( 2.1 ) • Be within close proximity to toilet facilities once administered. • Discontinue if treatment with opioid pain medication is also discontinued. • In adult patients with chronic non-cancer pain and OIC: o Patients receiving opioids for less than 4 weeks may be less responsive to RELISTOR. o Discontinue all maintenance laxative therapy before starting RELISTOR; may resume laxatives if there is a suboptimal response to RELISTOR after 3 days. o Re-evaluate the continued need for RELISTOR when opioid regimen is changed to avoid adverse reactions. • In patients with chronic non-cancer pain and OIC, take RELISTOR tablets with water on an empty stomach at least 30 minutes before the first meal of the day. Dosing • For OIC in adult patients with chronic non-cancer pain ( 2.2 ): o RELISTOR tablets: The recommended dosage is 450 mg once daily in the morning. o RELISTOR injection: The recommended dosage is 12 mg subcutaneously once d