3 known interactions • 0 major • 1 moderate • 2 minor
Always disclose all medications to your healthcare providers — prescription medicines, OTC medications, vitamins, and herbal supplements. This list may not include every possible interaction. Use our Medicine Interaction Checker to screen your complete medication list.
Potentially life-threatening or causing permanent damage. Avoid combination.
May worsen condition or require dose adjustment. Monitor closely.
Usually limited clinical effect. Manage with routine monitoring.
CNS depressants
Additive sedative effects
Management: Monitor for increased drowsiness
Antidiabetic medicines
May affect blood glucose control
Immunosuppressants
May enhance immune function
Always ask your pharmacist about potential interactions with food, alcohol, and supplements specific to Melatonin. Some medicines have significant interactions with grapefruit juice, high-fat meals, dairy products, or vitamin K-rich foods.