Complete dosing information for LINVOSELTAMAB-GCPT
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
2 DOSAGE AND ADMINISTRATION Premedicate to reduce the risk of CRS and infusion-related reactions (IRR). ( 2.1 , 2.3 ) Administer only as an intravenous infusion. ( 2.1 , 2.6 ) Recommended Dosage ( 2.2 ): Dosing Schedule Day Dose of LYNOZYFIC Step-Up Dosing Schedule Day 1 Step-up dose 1 5 mg Day 8 Step-up dose 2 25 mg Day 15 First treatment dose 200 mg Weekly Dosing Schedule One week after Day 15 treatment dose and once weekly from Week 4 to Week 13 for 10 treatment doses Second and subsequent treatment doses 200 mg Biweekly (Every 2 Weeks) Dosing Schedule Week 14 and every 2 weeks thereafter Subsequent treatment doses 200 mg Patients who have achieved and maintained VGPR or better at or after Week 24 and received at least 17 doses of 200 mg Every 4 Weeks Dosing Schedule At Week 24 or after and every 4 weeks thereafter Subsequent treatment doses 200 mg Patients should be hospitalized for 24 hours after administration of the first step-up dose and for 24 hours after administration of the