Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
6 ADVERSE REACTIONS The following adverse reactions have been identified post-approval.
Because these reactions are voluntarily reported from a population of uncertain size, it is not always possible to reliably estimate their exact frequency or establish a causal relationship to Technetium Tc 99m pentetate exposure.
Adverse reactions are presented in decreasing order of reported frequency: Immune system disorders: allergic reaction, anaphylactic reaction, angioedema.
Skin and subcutaneous tissue disorders: rash, itching, hives, erythema.
Respiratory, thoracic and mediastinal disorders: throat irritation, wheezing.
Vascular disorders: hypotension, hypertension.
Nervous system disorders: headache, fainting, dizziness.
General disorders and administration site conditions: chills.
Gastrointestinal disorders: nausea, vomiting.
Cardiac disorders: cyanosis, tachycardia.
5 WARNINGS AND PRECAUTIONS Hypersensitivity reactions: Hypersensitivity reactions, including anaphylaxis, have been reported during post-approval diagnostic use of Technetium Tc 99m pentetate injection.
Monitor all patients for hypersensitivity reactions ( 5.1 ).
Image interpretation risks in lung ventilation studies: If proximal airway deposition is observed, consider additional diagnostic options ( 5.2 ).
Radiation exposure risk: Technetium Tc 99m pentetate contributes to a patient’s overall long-term radiation exposure ( 2.1 , 2.3 , 5.3 ).
Bronchospasm in lung ventilation studies: Inhalation of Technetium Tc 99m pentetate solution may result in acute bronchoconstriction, especially in patients with heightened bronchoreactivity ( 5.4 ).
Like all medications, Kit For The Preparation Of Technetium Tc 99m Pentetate can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: