General MedicinePrescription OnlyPregnancy Cat. Not classifiedFDA Yes
Hyoscyamine Sulfate Sublingual
HYOSCYAMINE SULFATE SUBLINGUAL
This product may be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries and diverticulitis. It can also be used to control gastric secretion, visceral spasm and hypermotility in cystitis, pylorospasm and associated abdominal cramps. Along with appropriate analgesics, this product is indicated in symptomatic relief of biliary and renal colic and as a drying agent in the relief of symptoms of acute rhinitis. This product is effective as adjunctive ther...
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Brand names:Hyoscyamine Sulfate Sublingual
Quick Reference
Medicine ClassGeneral Medicine
FDA ApprovedYes
PregnancyCategory Not classified
Quick Facts
- Active ingredient
- HYOSCYAMINE SULFATE SUBLINGUAL
- Medicine class
- General Medicine
- Brand names
- Hyoscyamine Sulfate Sublingual
- Availability
- Prescription only (Rx)
- Pregnancy category
- Not classified
- FDA approved
- Yes
Medical Review
Medically reviewed- Reviewed by
- MedCentralHub Medical Review Board
- Credentials
- Licensed Pharmacists & Physicians
- Last reviewed
- Next review
Written from primary sources (FDA labeling, NIH/MedlinePlus, peer-reviewed literature) and verified by our review board. Educational information only — not a substitute for professional medical advice. See our medical disclaimer.
What Is Hyoscyamine Sulfate Sublingual?
This product may be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries and diverticulitis. It can also be used to control gastric secretion, visceral spasm and hypermotility in cystitis, pylorospasm and associated abdominal cramps. Along with appropriate analgesics, this product is indicated in symptomatic relief of biliary and renal colic and as a drying agent in the relief of symptoms of acute rhinitis. This product is effective as adjunctive ther...
Hyoscyamine Sulfate Sublingual (HYOSCYAMINE SULFATE SUBLINGUAL) belongs to the General Medicine class of medications. It was first approved by the FDA in Yes. This medication requires a prescription from a licensed healthcare provider.
Key Safety Information
- •Always follow the dose recommended by your healthcare professional. Taking more than prescribed increases the risk of side effects including serious complications.
- •Seek emergency care if you experience signs of an allergic reaction — hives, swelling, difficulty breathing, or rash. Stop the medication and call your doctor immediately.
- •Some medications can increase the risk of cardiovascular events. Tell your doctor if you have high blood pressure, a history of heart attack or stroke, or any pre-existing health condition.
- •Avoid or limit alcohol while taking Hyoscyamine Sulfate Sublingual. Do not drink alcohol without first discussing it with your healthcare provider as it may increase adverse effects.
- •Take Hyoscyamine Sulfate Sublingual with food or a full glass of water if stomach upset occurs. Stop use and talk to your doctor if you experience persistent stomach pain or GI symptoms.
- •Tell your doctor about all medications, supplements, and vitamins you take. Some combinations significantly increase the risk of harm.
This is a summary only. Always read the full prescribing information and consult your healthcare provider for personalized medical advice.
Uses & Indications
Hyoscyamine Sulfate Sublingual is prescribed for the following conditions. Some uses are FDA-approved indications; others may be evidence-based off-label uses. Consult your healthcare provider for personalized guidance.
This product may be used in functional intestinal disorders to reduce symptoms such as those seen in mild dysenteries and diverticulitis.
It can also be used to control gastric secretion, visceral spasm and hypermotility in cystitis, pylorospasm and associated abdominal cramps.
Along with appropriate analgesics, this product is indicated in symptomatic relief of biliary and renal colic and as a drying agent in the relief of symptoms of acute rhinitis.
This product is effective as adjunctive therapy in the treatment of peptic ulcer and irritable bowel syndrome, acute enterocolitis and other functional gastrointestinal disorders.
Dosage Guide
The following are general dosing guidelines only. Your actual dose should be determined by your healthcare provider based on your condition, renal/hepatic function, and other medications.
AD
Adult Dosage
Dosage may be adjusted according to the condition and severity of symptoms. May be taken with or without water. Adults and adolescents 12 years of age and older:1 to 2 tablets sublingually three or four times a day, thirty minutes to one hour before meals and at bedtime. Dosage may be increased to every four hours as needed. Do not exceed 12 tablets in 24 hours. Note:Geriatric patients may be more sensitive to the effects of the usual adult dose.
Available Forms
Available Strengths
Side Effects
Common
- Not all of the following adverse reactions have been reported with hyoscyamine sulfate.
- The following adverse reactions have been reported for pharmacologically similar drugs with anticholinergic/ antispasmodic action.
- Adverse reactions may include dryness of the mouth, urinary hesitancy and retention;
- blurred vision;
- tachycardia;
- palpitations;
- cycloplegia;
Serious
- Heat prostration can occur with drug use in the event of high environmental temperature.
- Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy;
- in this instance, treatment would be inappropriate and possibly harmful.
- This product may cause drowsiness or blurred vision.
- Patients taking this product should be warned not to engage in activities requiring mental alertness such as operating a motor vehicle or other machinery or to perform hazardous tasks while taking this drug.
Rare
Medicine Interactions
Always inform your healthcare provider and pharmacist about ALL medications you take, including prescriptions, OTC medicines, vitamins, and supplements.
MajorModerateMinor
Warnings & Contraindications
Heat prostration can occur with drug use in the event of high environmental temperature. Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy; in this instance, treatment would be inappropriate and possibly harmful. This product may cause drowsiness or blurred vision.
How Hyoscyamine Sulfate Sublingual Works
Pharmacokinetics
Pregnancy & Breastfeeding Safety
Not classified
Breastfeeding
Many medications pass into breast milk in varying amounts. Before using Hyoscyamine Sulfate Sublingualwhile breastfeeding, discuss the benefits and risks with your healthcare provider or pharmacist — they can weigh your dose, your infant's age, and available lactation safety data to find the safest option for you and your baby.
Storage & Handling
Dispense in a tight, light-resistant container as defined in USP/NF, with a child-resistant closure. Store at controlled room temperature between 20°-25°C (68°-77°F), see USP Controlled Room Temperature. KEEP THIS AND ALL MEDICATION OUT OF THE REACH OF CHILDREN. IN CASE OF ACCIDENTAL OVERDOSE, SEEK
Frequently Asked Questions
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Sources & References
- • FDA Prescribing Information — Official labeling and package insert for Hyoscyamine Sulfate Sublingual
- • U.S. National Library of Medicine — MedlinePlus drug information
- • American Hospital Formulary Service (AHFS) — Clinical pharmacology monograph
- • PubMed / MEDLINE — View clinical studies
Last reviewed by MedCentralHub Medical Review Board · MedCentralHub Editorial Policy
Sources & References
Content on this page is drawn from the following primary sources and reviewed against current labeling.
- FDA DailyMed — Official FDA prescribing information and drug labels
- MedlinePlus (NIH) — Patient-friendly drug information from the National Library of Medicine
- FDA Drug Safety Communications — Current FDA safety alerts, recalls, and label changes
- PubMed — Peer-reviewed clinical literature
Medical Disclaimer
The information on this page is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult your doctor, pharmacist, or qualified healthcare provider before starting, stopping, or changing any medication.