Complete dosing information for ESTRADIOL GEL 0.1%
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
2 DOSAGE AND ADMINISTRATION Daily administration of 0.25 to 1.25 grams of estradiol gel 0.1% to the right or left upper thigh on alternating days. Women should be started with the lowest effective dose and the dose should be evaluated periodically ( 2 ). 2.1 Important Use Information The timing of estradiol gel 0.1% initiation can affect the overall benefit-risk profile. Consider initiating estradiol gel 0.1% in women <60 years old or <10 years since menopause onset [see Warnings and Precautions ( 5 ), Use in Specific Populations ( 8.5 ) and Clinical Studies ( 14 )]. When estrogen is prescribed for a menopausal woman with a uterus, the addition of a progestogen has been shown to reduce the risk of endometrial cancer. There are possible risks associated with the use of progestogens plus estrogens that differ from those of estrogen-alone regimens. See prescribing information for progestogens indicated for the prevention of endometrial hyperplasia in non-hysterectomized menopausal women