Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
6 ADVERSE REACTIONS The following clinically significant adverse reactions are discussed in greater detail in other sections of the labeling: • Myelosuppression [see Dosage and Administration (2.5) and Warnings and Precautions (5.1) ] .
• Bleeding-related events [see Warnings and Precautions (5.2) ] .
• Fluid retention [see Warnings and Precautions (5.3) ] .
• Cardiovascular toxicity [see Warnings and Precautions (5.4) ] .
• Pulmonary arterial hypertension [see Warnings and Precautions (5.5) ] .
• QT prolongation [see Warnings and Precautions (5.6) ] .
• Severe dermatologic reactions [see Warnings and Precautions (5.7) ] .
• Tumor lysis syndrome [see Warnings and Precautions (5.8) ] .
• Effects on growth and development in pediatric patients [see Warnings and Precautions (5.10) ] .
• Hepatotoxicity [see Warnings and Precautions (5.11) ] .
5 WARNINGS AND PRECAUTIONS Myelosuppression and Bleeding Events: Severe thrombocytopenia, neutropenia, and anemia may occur.
Use caution if used concomitantly with medications that inhibit platelet function or anticoagulants.
Monitor complete blood counts regularly.
Transfuse and interrupt dasatinib tablets when indicated.
( 2.5 , 5.1 , 5.2 ) Fluid Retention: Fluid retention, sometimes severe, including pleural effusions.
Like all medications, Dasatinib can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: