Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
ADVERSE REACTIONS See BOXED WARNINGS , WARNINGS , and PRECAUTIONS .
Premarin Intravenous for injection is indicated for short-term use.
However, the warnings, precautions and adverse reactions associated with oral Premarin treatment should be taken into account.
The following adverse reactions have been identified during post-approval use of oral or intravenous Premarin.
Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Genitourinary system Abnormal uterine bleeding/spotting.
Dysmenorrhea or pelvic pain.
Increase in size of uterine leiomyomata.
Vaginitis, including vaginal candidiasis.
Change in amount of cervical secretion.
WARNINGS See BOXED WARNINGS .
Premarin Intravenous for injection is indicated for short-term use.
However, warnings, precautions and adverse reactions associated with oral Premarin treatment should be taken into account.
Cardiovascular Disorders An increased risk of stroke and DVT has been reported with estrogen-alone therapy.
An increased risk of PE, DVT, stroke, and MI has been reported with estrogen plus progestin therapy.
Like all medications, Premarin can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: