No black box warning on record for D-28
As of the latest FDA labeling reviewed, D-28 (CLAVICEPS PURPUREA SCLEROTIUM, HAMAMELIS VIRGINIANA ROOT BARK/STEM BARK, SAFFRON, FERROSOFERRIC PHOSPHATE, SULFURIC ACID, AND HORSE CHESTNUT) does not carry a black box warning. Standard warnings and precautions still apply — see the full D-28 medicine page for the complete safety profile.