General MedicineOTC AvailablePregnancy Cat. Not classifiedFDA Yes
Alka-Seltzer Plus Cold And Flu Fizzychews
CHLORPHENIRAMINE MALEATE, ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE
Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · runny nose · sneezing · sore throat · temporarily reduces fever
Medically reviewed by MedCentralHub Medical Review Board, Licensed Pharmacists & Physicians ·
Brand names:Alka-Seltzer Plus Cold and Flu FizzyChews
Quick Reference
Medicine ClassGeneral Medicine
FDA ApprovedYes
PregnancyCategory Not classified
Quick Facts
- Active ingredient
- CHLORPHENIRAMINE MALEATE, ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE
- Medicine class
- General Medicine
- Brand names
- Alka-Seltzer Plus Cold and Flu FizzyChews
- Availability
- Over-the-counter (OTC)
- Pregnancy category
- Not classified
- FDA approved
- Yes
Medical Review
Medically reviewed- Reviewed by
- MedCentralHub Medical Review Board
- Credentials
- Licensed Pharmacists & Physicians
- Last reviewed
- Next review
Written from primary sources (FDA labeling, NIH/MedlinePlus, peer-reviewed literature) and verified by our review board. Educational information only — not a substitute for professional medical advice. See our medical disclaimer.
What Is Alka-Seltzer Plus Cold And Flu Fizzychews?
Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · runny nose · sneezing · sore throat · temporarily reduces fever
Alka-Seltzer Plus Cold And Flu Fizzychews (CHLORPHENIRAMINE MALEATE, ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE) belongs to the General Medicine class of medications. It was first approved by the FDA in Yes. This medication is available over-the-counter without a prescription.
Key Safety Information
- •Always follow the dose recommended by your healthcare professional. Taking more than prescribed increases the risk of side effects including serious complications.
- •Seek emergency care if you experience signs of an allergic reaction — hives, swelling, difficulty breathing, or rash. Stop the medication and call your doctor immediately.
- •Some medications can increase the risk of cardiovascular events. Tell your doctor if you have high blood pressure, a history of heart attack or stroke, or any pre-existing health condition.
- •Avoid or limit alcohol while taking Alka-Seltzer Plus Cold And Flu Fizzychews. Do not drink alcohol without first discussing it with your healthcare provider as it may increase adverse effects.
- •Take Alka-Seltzer Plus Cold And Flu Fizzychews with food or a full glass of water if stomach upset occurs. Stop use and talk to your doctor if you experience persistent stomach pain or GI symptoms.
- •Tell your doctor about all medications, supplements, and vitamins you take. Some combinations significantly increase the risk of harm.
This is a summary only. Always read the full prescribing information and consult your healthcare provider for personalized medical advice.
Uses & Indications
Alka-Seltzer Plus Cold And Flu Fizzychews is prescribed for the following conditions. Some uses are FDA-approved indications; others may be evidence-based off-label uses. Consult your healthcare provider for personalized guidance.
Uses · temporarily relieves these symptoms due to a cold or flu: · minor aches and pains · headache · cough · runny nose · sneezing · sore throat · temporarily reduces fever
Dosage Guide
The following are general dosing guidelines only. Your actual dose should be determined by your healthcare provider based on your condition, renal/hepatic function, and other medications.
AD
Adult Dosage
Directions · do not take more than the recommended dose · adults and children 12 years and over: take 2 tablets every 4 hours. Do not exceed 12 tablets in 24 hours or as directed by a doctor. · do not swallow tablets whole. Chew or crush tablets completely before swallowing. · children under 12 years: do not use
Available Forms
Available Strengths
Side Effects
Common
Serious
- Warnings Liver warning: This product contains acetaminophen.
- Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions.
- Symptoms may include: · skin reddening · blisters · rash · hives · facial swelling · asthma (wheezing) · shock If a skin or general allergic reaction occurs, stop use and seek medical help right away.
- Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
- Do not use to sedate children Do not use ● with any other drug containing acetaminophen (prescription or nonprescription).
Rare
Medicine Interactions
Always inform your healthcare provider and pharmacist about ALL medications you take, including prescriptions, OTC medicines, vitamins, and supplements.
MajorModerateMinor
Warnings & Contraindications
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take · more than 4,000 mg of acetaminophen in 24 hours · with other drugs containing acetaminophen · 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin or severe allergic reactions.
How Alka-Seltzer Plus Cold And Flu Fizzychews Works
Pharmacokinetics
Pregnancy & Breastfeeding Safety
Not classified
Breastfeeding
Many medications pass into breast milk in varying amounts. Before using Alka-Seltzer Plus Cold And Flu Fizzychewswhile breastfeeding, discuss the benefits and risks with your healthcare provider or pharmacist — they can weigh your dose, your infant's age, and available lactation safety data to find the safest option for you and your baby.
Storage & Handling
Store at room temperature. Keep away from moisture and heat. Keep out of reach of children.
Frequently Asked Questions
Related on MedCentralHub
- Class hub
General Medicine alternatives
Compare all General Medicine medications — uses, side effects, and cost differences
- Detail
Alka-Seltzer Plus Cold And Flu Fizzychews dosage guide
Adult, pediatric, renal, and hepatic dosing for Alka-Seltzer Plus Cold And Flu Fizzychews
- Detail
Alka-Seltzer Plus Cold And Flu Fizzychews side effects
Complete adverse effect profile including common, serious, and rare reactions
- Topic
InteractGuard
- Topic
FDA Alerts & Recalls
- Topic
FDA Approvals
- Topic
Medicine Safety Guide
- Topic
Pregnancy Safety
- Topic
Pediatric Dosing
Sources & References
- • FDA Prescribing Information — Official labeling and package insert for Alka-Seltzer Plus Cold And Flu Fizzychews
- • U.S. National Library of Medicine — MedlinePlus drug information
- • American Hospital Formulary Service (AHFS) — Clinical pharmacology monograph
- • PubMed / MEDLINE — View clinical studies
Last reviewed by MedCentralHub Medical Review Board · MedCentralHub Editorial Policy
Sources & References
Content on this page is drawn from the following primary sources and reviewed against current labeling.
- FDA DailyMed — Official FDA prescribing information and drug labels
- MedlinePlus (NIH) — Patient-friendly drug information from the National Library of Medicine
- FDA Drug Safety Communications — Current FDA safety alerts, recalls, and label changes
- PubMed — Peer-reviewed clinical literature
Medical Disclaimer
The information on this page is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult your doctor, pharmacist, or qualified healthcare provider before starting, stopping, or changing any medication.