Complete dosing information for C1 ESTERASE INHIBITOR RECOMBINANT
Medical guidance required: Dosing information here is for educational purposes. Your healthcare provider will determine the appropriate dose based on your specific condition, kidney function, other medications, and medical history. Never adjust your dose without consulting your doctor or pharmacist.
2 DOSAGE AND ADMINISTRATION For intravenous use after reconstitution only. For Intravenous Use Only. Reconstitute each vial (2100 U) by adding 14 mL sterile Water for Injection per vial to obtain a solution of 150 U per mL. ( 2.3 ) Administer the reconstituted solution at room temperature as a slow intravenous injection over approximately 5 minutes. ( 2.4 ) Appropriately trained patients may self-administer upon recognition of an HAE attack. ( 2.4 ) Recommended dose of RUCONEST for an acute attack Body weight RUCONEST Dose for Intravenous Injection Volume (mL) of Reconstituted Solution (150 U/mL) to be Administered < 84 kg 50 U per kg Body weight in kg divided by 3 ≥ 84 kg 4200 U (2 vials) 28 mL If the attack symptoms persist, an additional (second) dose can be administered at the recommended dose level. Do not exceed 4200 U per dose. No more than two doses should be administered within a 24-hour period. 2.1 Recommended Dosing Training on how to administer RUCONEST should be conducted