3 known interactions • 3 major • 0 moderate • 0 minor
Always disclose all medications to your healthcare providers — prescription medicines, OTC medications, vitamins, and herbal supplements. This list may not include every possible interaction. Use our Medicine Interaction Checker to screen your complete medication list.
Potentially life-threatening or causing permanent damage. Avoid combination.
May worsen condition or require dose adjustment. Monitor closely.
Usually limited clinical effect. Manage with routine monitoring.
Carbamazepine
Significant reduction in bictegravir levels
Management: Avoid combination or use alternative anticonvulsant
Rifampin
Significant reduction in bictegravir levels
Management: Avoid combination
St. John's Wort
Reduction in bictegravir levels
Management: Avoid concurrent use
Always ask your pharmacist about potential interactions with food, alcohol, and supplements specific to Biktarvy. Some medicines have significant interactions with grapefruit juice, high-fat meals, dairy products, or vitamin K-rich foods.