No black box warning on record for D-27
As of the latest FDA labeling reviewed, D-27 (BERBERIS VULGARIS ROOT BARK, NITRIC ACID, CALCIUM FLUORIDE, LYCOPODIUM CLAVATUM SPORE, RUBIA TINCTORUM ROOT, AND SMILAX ORNATA ROOT) does not carry a black box warning. Standard warnings and precautions still apply — see the full D-27 medicine page for the complete safety profile.