No black box warning on record for Refill 2
As of the latest FDA labeling reviewed, Refill 2 (BENZALKONIUM CHLORIDE, BACITRACIN ZINC, NEOMYCIN SULFATE, POLYMYXIN B SULFATE) does not carry a black box warning. Standard warnings and precautions still apply — see the full Refill 2 medicine page for the complete safety profile.