Complete adverse effect profile including incidence rates and management
Important Safety Information
This is not a complete list of all possible side effects. Contact your healthcare provider if you experience any unexpected symptoms. For serious or life-threatening side effects, seek emergency medical attention immediately.
ADVERSE REACTIONS Aminocaproic acid is generally well tolerated.
The following adverse experiences have been reported: General : Edema, headache, malaise.
Hypersensitivity Reactions : Allergic and anaphylactoid reactions, anaphylaxis.
Local Reactions : Injection site reactions, pain and necrosis.
Cardiovascular : Bradycardia, hypotension, peripheral ischemia, thrombosis.
Gastrointestina l: Abdominal pain, diarrhea, nausea, vomiting.
Hematologic : Agranulocytosis, coagulation disorder, leukopenia, thrombocytopenia.
Musculoskeletal : CPK increased, muscle weakness, myalgia, myopathy (see WARNINGS ), myositis, rhabdomyolysis.
Neurologic : Confusion, convulsions, delirium, dizziness, hallucinations, intracranial hypertension, stroke, syncope.
Respiratory: Dyspnea, nasal congestion, pulmonary embolism.
WARNINGS Aminocaproic Acid Injection, USP contains benzyl alcohol as a preservative.
The administration of medications containing benzyl alcohol as a preservative to premature neonates has been associated with a fatal “Gasping Syndrome”.
(See PRECAUTIONS, Pediatric Use.
) In patients with upper urinary tract bleeding, aminocaproic acid administration has been known to cause intrarenal obstruction in the form of glomerular capillary thrombosis or clots in the renal pelvis and ureters.
For this reason, aminocaproic acid should not be used in hematuria of upper urinary tract origin, unless the possible benefits outweigh the risk.
Like all medications, Aminocaproic Acid can cause side effects. However, not everyone who takes this medication will experience them. Many side effects are dose-dependent and may improve as your body adjusts to the medication. Others may require dose adjustment or medical attention.
Contact your healthcare provider promptly if you experience:
Seek immediate emergency medical care if you experience signs of: